Edema and Related Medical Conditions

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Sunday, October 21, 2012

Early bilateral cystoid macular oedema secondary to fingolimod in multiple sclerosis.

Early bilateral cystoid macular oedema secondary to fingolimod in multiple sclerosis.



Department of Ophthalmology, Royal United Hospital Bath, Bath BA1 3NG, UK.


We report a case of fingolimod-associated bilateral cystoid macular oedema in a patient with multiple sclerosis (MS). A 34-year-old female, diagnosed with MS at age of 30, developed bilateral blurred vision 5 days after initiation of fingolimod. She was misdiagnosed as optic neuritis initially and fingolimod was only discontinued 3 weeks after onset of her visual symptoms when OCT showed prominent bilateral cystoid macular oedema and subretinal fluid. Although her left corrected vision returned to 6/6, she had persistently decreased right visual acuity of 6/12 after 5 months. This paper aims to raise awareness among ophthalmologists and neurologists of the importance of early recognition of macular oedema associated with fingolimod.

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