Edema and Related Medical Conditions

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Saturday, September 01, 2012

Several new treatment possibilities of hereditary angio-oedema.

Several new treatment possibilities of hereditary angio-oedema.

August 2012

[Article in Danish]


Hudafdeling I, Odense Universitetshospital, Sdr. Boulevard 29, 5000 Odense C. anne.aabom@ouh.regionsyddanmark.dk.


Hereditary angio-oedema (HAE) is a rare genetic disease caused by deficiency of complement C1 inhibitor. It is characterised by recurrent episodes of subcutaneous or submucosal oedema typically involving the extremities, bowel, face or larynx. Within the latest years it has become evident that the active mediator of HAE attacks is an increased level of bradykinin and various new treatment modalities have been developed. The aim of this paper is to give an update from the Danish HAE Comprehensive Care Centre on current treatment possibilities and address some of the challenges when diagnosing HAE.

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