Chandler's Syndrome and Corneal Edema

Synonyms

Dystrophia Endothelialis Cornea
Iris Atrophy with Corneal Edema and Glaucoma

Disorder Subdivisions

None

General Discussion

Chandler's syndrome (CS) is a rare eye disorder in which the single layer of cells lining the interior of the cornea proliferates, causing the drying up of the iris, corneal swelling, and unusually high pressure in the eye (glaucoma). CS is one of three syndromes affecting the eyes (progressive iris atrophy and Cogan-Reese syndrome are the other two) that make up the iridocorneal endothelial syndrome. Chandler’s syndrome affects females more often than males and usually presents sometime during middle age. Most often the condition affects one eye only but if it is not treated, with time, the second eye may become involved. The combination of high pressure within the eye (glaucoma) and leaking of fluid through the cellular membrane can result in reduced vision with pain..

Resources

National Association for Visually Handicapped, 22 West 21st StreetNew York, NY 10010,USATel: 2128893141, Fax: 2127272931
Email: staff@navh.org

Schepens Eye Research Institute 20 Staniford StreetBoston, MA 02114-2500, Tel: (617)912-0100, Fax: (617)523-3463
Email: geninfo@vision.eri.harvard.edu

National Association for Parents of Children with Visual Impairments (NAPVI) P.O. Box 317 Watertown, MA 02472, Tel: (617)972-7441, Fax: (617)972-7444, Tel: (800)562-6265
Email: napvi@perkins.org

Prevent Blindness America 500 East Remington Road, Schaumberg, IL 60173, Tel: (847)843-2020, Fax: (847)843-8458, Tel: (800)331-2020
Email: info@preventblindness.org

NIH/National Eye Institute Building 31 Rm 6A3231 Center Dr MSC 2510, Bethesda, MD 20892-2510, United States, Tel: 3014965248, Fax: 3014021065
Email: 2020@nei.nih.gov